The U.S. Food and Drug Administration, Washington DC.
The (FDA) is strengthening an existing label warning that non-aspirin anti-inflammatory drugs (NSAIDs) increase the chance of a heart attack or stroke.
Based on our comprehensive review of new safety information, we are requiring updates to the drug labels of all prescription NSAIDs like aspirin, Motrin, Advil, Celebrex and many others.
There is an increased risk of heart failure with NSAID use.
The risk of heart attack or stroke can occur as early as the first weeks of using an NSAID.
The risk may increase with longer use of the NSAID.
Patients and health care professionals should remain alert for heart-related side effects the entire time that NSAIDs are being taken.